MYOTONIN PROTEIN KINASE (MtPK) AFFECTS THE CHLORIDE PERMEABILITY OF C2C12 MYOGENIC CELLS
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چکیده
منابع مشابه
Phosphorylation of Staphylococcus aureus Protein-Tyrosine Kinase Affects the Function of Glucokinase and Biofilm Formation
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متن کاملFull-length myotonin protein kinase (72 kDa) displays serine kinase activity.
We describe the full-length (72 kDa) myotonin protein kinase (Mt-PK) and demonstrate its kinase activity. The 72-kDa protein corresponds to the translation product from the first in-frame AUG codon. This protein was found in the cytoplasmic fraction, whereas the previously reported 55-kDa protein was observed in nuclear extracts. Only the 72-kDa protein was phosphorylated by [32P]phosphate in n...
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Myf-5 and MyoD are members of a family of musclespecific basic helix-loop-helix (bHLH) proteins that are fundamental for myogenic cell differentiation and transcriptional activation of muscle-specific genes. Here we report that elevated levels of the intracellular signaling molecule CAMP and overexpression of CAMP-dependent protein kinase (PKA) inhibit myogenic differentiation. PKA represses...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 1998
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.19.191